System

Impact of Biofilm Formation

References

General Persistent infections Costerton et al., Science 284:1318-1322 (1999)

Potera, Science 283:1837 (1999)

J. California Dental Association 29(5):347-369 (2001)

Costerton and Stewart, Scientific Amer. 285(1):74-81 (2001)

Hall-Stoodley et al, Nature Reviews Microbiology, 2(2):95-108 (2004)

Dental plaque Caries, gingivitis, periodontitis Marsh and Bradshaw, J. Ind. Microbiol 15:169 (1995)

Darveau et al, Periodontal 2000 14:12 (1997)

Page et al, Periodontal 2000 14:216
Chronic infections

- Otitis media
- Cystic fibrosis
pneumonia
- Biliary tract
infections
- Osteomyelitis
- Bacterial
prostatitis
- Native heart
valve
- Urinary tract
- Diabetic foot ulcers
- Decubitis ulcers
- Venous leg ulcers
- Sinusitis (?)
- Tonsilitis (?)

 

Persistent infection Fux et al, TRENDS in Microbiology 13(1):34-40 (2005)

Donlan, Emerging Infect Dis., 7(2):277-281 (2001)

Ehrlich, et al, ASM News, 70(3):127-133 (2004)

Percival and Bowler, Wounds 16(7):234-239 (2004)

 

Catheters

- Urinary
- Vascular
- Central venous
- Hickman
- Swan-Ganz
- Periotoneal dialysis
(Tenckhoff)

 

Contamination, drain blockage, endocarditis Fux et al, Expert Rev. Anti-infect. Ther., 1(4):89-105 (2003).

 

Implanted devices

- Contact lenses
- Biliary stents
- Orthopedic devices
- Prosthetic heart
valves
- Cardiac
pacemakers
- IUDs
- Endotrachial tubes
- Nasogastric tubes
- Hemodialysis units

Contamination,
infection